Yet Eisenhower concluded the war as a five-star general, the architect of Operation Overlord-the allied invasion of Normandy-and the indispensable man who had balanced the interests and egos of a galaxy of generals and political leaders.īalance and mission would distinguish Eisenhower’s presidency in the 1950s. When Japan bombed Pearl Harbor, on December 7, 1941, bringing the United States into the conflagration, he had been promoted to a one-star brigadier general only a few short months before. When German and Soviet tanks rumbled across Poland to start the war in September 1939, Ike had been a mere lieutenant colonel (and a major, stuck in rank for 12 consecutive years before that). It also marked an amazing achievement for Eisenhower himself. Eisenhower.” It was the end of World War II in Europe, a victory then as now venerated by millions. Seventy-five years ago, the supreme allied commander of the Allied Expeditionary Force dictated a message simple and sublime: “The mission of this Allied force was fulfilled at 0241, local time, May 7, 1945.
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These links between damage to the genetic code and other pillars of aging support the notion that DNA damage could be the root of aging. We also provide evidence that genotoxic stress is linked to other cellular processes implicated as drivers of aging, including mitochondrial and metabolic dysfunction, altered proteostasis and inflammation. Here, we review evidence that DNA damage plays a causal role in aging. The drawback is that these cancer avoidance mechanisms promote aging. Persistent DNA damage (genotoxic stress) triggers signaling cascades that drive cells into apoptosis or senescence to avoid replicating a damaged genome. To combat this, all organisms possess highly conserved mechanisms to detect and repair DNA damage. DNA damage is a constant threat because nucleic acids are chemically unstable under physiological conditions and vulnerable to attack by endogenous and environmental factors. The integrity of the nuclear genome is essential for cellular, tissue, and organismal health. Many factors contribute to aging, such as the time-dependent accumulation of macromolecular damage, including DNA damage. Aging is a complex process that results in loss of the ability to reattain homeostasis following stress, leading, thereby, to increased risk of morbidity and mortality. He writes with wit, with heartbreaking dignity, and with the simplicity of a great artist in full control of his art. Le Guin gave Saramago's Seeing high praise, noting that, "He has written a novel that says more about the days we are living in than any book I have read. Seeing received generally positive reviews. Some of the characters from Blindness appear in the second half of the novel, including 'the doctor' and 'the doctor's wife', and the 'dog of tears' now with the name, Constant. The first half of the story focuses on the struggles of the government and its various nameless members as they try to simultaneously understand and destroy the amorphous non-movement of blank-voters. The story begins with a parliamentary election, in which the majority (83%) of the populace cast blank ballots. Seeing is set in the same unnamed country featured in Blindness. Seeing is the sequel to one of Saramago's most famous works, Blindness. The book was published in Portuguese in 2004 and then in English in 2006. Essay on Lucidity) is a novel by the Nobel Prize-winning Portuguese author José Saramago. Seeing ( Portuguese: Ensaio sobre a Lucidez, lit. The main character, Dorian Gray, is painted by the artist Basil Hallward. It is somewhat reminiscent of Nathaniel Hawthorne's short story, The Prophetic Pictures. The story itself has a strong Faustian theme (making a deal with the devil in exchange for earthly gain or pleasure). Books are well written, or badly written. The 1891 text contained significant alterations new chapters were added, controversial material was dropped, and other alterations were made, including the addition of The Preface where Wilde stated, "There is no such thing as a moral or an immoral book. He rewrote the story for an April 1891 publication. Ultimately, WIlde was force to yield some ground. The reaction was so strong that many critics wanted Wilde prosecuted for a failure of morality and Wilde was forced to defend himself vigorously in the press. Even with those modifications the publication was greeted with great outrage. Fearing that the work would be perceived as indecent, the editors at Lippincott's censored about 500 words without Wilde's knowledge. The novel - the only one that Oscar Wilde published - was very controversial for its times. The work was first published in Lippincott's Monthly Magazine on June 20, 1890. The Picture of Dorian Gray is a fine example of classical Gothic fiction. It’s that which “helps the mourner begin to heal. She visited glass coffins in Spain a crematorium in Japan, where nearly all residents are cremated and Bolivia, where skulls are said to dispense advice. And everywhere, she saw “grief, unimaginable grief. She went to Mexico, where she met a grieving young mother who “just wanted to engage with death … frequent it, mock it, caress it.”ĭoughty’s travels took her to North Carolina, and a new method of body disposal. She wanted to show that there is no one, correct way to understand or deal with the deaths of our loved ones. Doughty, herself a funeral home owner, was inspired to witness how death is dealt with in other cultures. In Indonesia, Doughty visited cliffside graves with “a scholar of the macabre,” who also took her to a village where people live with (and sometimes sleep next to) their dead –perhaps for years. From Here To Eternity by Caitlin Doughty is a fascinating look at funerary practices from around the world. In a tiny town in Colorado, she visited “the only community open-air pyre in America.” Its founders worked hard to gain acceptance from locals and to change laws regarding open-air cremation today, people relocate in order to take advantage of the pyre. And so, she went in search of a “good death.” And I think that was the first thing that struck me about ‘Crave’. And as Grace is drawn further under his spell, she begins to wonder: did she come to Katmere by accident, or was she brought here. Something in him calls to Grace - something that could spell her death.īecause Jaxon walled himself off for a reason. Then she meets Jaxon Vega, a vampire with deadly secrets who hasn't felt anything for a hundred years. As the lone mortal, the only thing Grace is sure of is that she doesn't belong. Shapeshifters, witches and vampires roam the halls, existing in uneasy cooperation. Soon she realises she's entered a world like nothing she has ever known. Her uncle's exclusive and secretive boarding school is the last place she wants to be, but after the tragic deaths of both her parents, she is left with no choice. The moment she steps foot inside, Grace knows there is nothing normal about Katmere Academy, or the students in it. In case you missed the TikTok buzz over this, here’s what’s it’s all about: That to me was a selling point, and how I sold it to my sister. I mean, that is largely to do with the fact that it reads a little like ‘Twilight’ fanfic, but that’s not a criticism. ‘Crave’ is one of the books that felt like a similar experience. He had a well furnished room, dined well, put on theatrical productions and was visitted by the Abbe Coulmier. (The guillotine really was moved behind a jail when the Parisians began complaining about the smell.)ĭe Sade, who was arrested for sodomy and kidnapping before his writing landed him in trouble, spent his last years in an insane asylum because his wife's family preferred that to prison. Slowly, we realize that that man is an executioner and that we are seeing a woman at the guillotine just as De Sade is, gazing out of his prison window. As the Marquis tells the tale of a noblewoman with a taste for pain, we see that woman responding to the hands and kiss of her lover. Kaufman startles us right at the onset of his film. The art of writing isn't the most visual one, yet Kaufman, who tackled writers before in "Henry and June," succeeds with his provoking film "Quills." Maybe its because he's chosen authors of controversial works laden with sex, but here, at least, his film works because it gets his audience thinking - does the reading of De Sade's books cause humans to behave badly or does the censorship of his work create the evil atmosphere? Will the sleeping beauty be able to wake herself up?ĭisney Twisted Tales: A Whole New World NovelĪ new series of YA Novels that re-imagine classic Disney stories in surprising new ways. But with Maleficent's agents following her every move, Aurora struggles to discover who her true allies are, and more importantly, who she truly is. Soon she stumbles upon Phillip, a charming prince eager to join her quest. With a desperate fairy's last curse infiltrating her mind, Princess Aurora will have to navigate a dangerous magical landscape deep in the depths of her dreams. But when said prince falls asleep as soon as his lips meet the princess's, it is clear that this fairy tale is far from over. What if the sleeping beauty never woke up? It should be simple - a dragon defeated, a slumbering maiden, a prince poised to wake her. Gilman theorizes that the structure can enable travel from one plane or dimension to another. The dimensions of Gilman's attic room are unusual and seem to conform to a kind of unearthly geometry. Gilman discovers that, for the better part of two centuries, many of the attic's occupants have died prematurely. The house once harboured Keziah Mason, an accused witch who disappeared mysteriously from a Salem jail in 1692. Walter Gilman, a student of mathematics and folklore at Miskatonic University, rents an attic room in the "Witch House", a house in Arkham, Massachusetts, that is rumored to be cursed. It was written in January/February 1932 and first published in the July 1933 issue of Weird Tales. Lovecraft, part of the Cthulhu Mythos cycle. " The Dreams in the Witch House" is a horror short story by American writer H. The Dreams in the Witch House at Wikisource For the Masters of Horror episode, see H. " novel of epiphanies, tragedies, and transformations. Before long, tension and suspicion reign, and this close-knit community must reckon with questions of faith, fear, and forgiveness. With uncompromising fervor (and with a new pit bull named John the Baptist), Stew Pot soon appoints himself the moral judge of Parkland-and starts wreaking havoc on people's lives. Motley, a widowed retired librarian and the Reeves' next-door neighbor, who loans Stew Pot a Bible, which is seen by him and many in the community as a friendly gesture. Most folks are skeptical, with one notable exception: Mrs. The anxiety only grows when Stew Pot announces that he experienced a religious awakening in prison. The residents are in a tailspin, dreading the arrival of the man they remember as a frightening delinquent. One of Roxane Gay's Top 10 Books of the YearĪfter fourteen years in prison, Gerald "Stew Pot" Reeves, age thirty-one, returns home to live with his mom in Parkland, a black middle-class neighborhood on Chicago's South Side. One of Booklist 's Top 10 First Novels of the Year An ex-convict returns to his Chicago community a changed man-but maybe not for the better-in this "vivid, suspenseful, funny, and compassionate novel" ( Booklist). |